What is the significance of a "clue cell" found in wet mount examination?

A clue cell is a type of epithelial cell coated with bacteria, primarily associated with bacterial vaginosis (BV). During a wet mount examination, the presence of clue cells indicates a shift in the normal vaginal flora, demonstrating a decrease in lactobacilli and an overgrowth of other bacterial species. This condition is characterized by a fishy odor, often more noticeable after intercourse or menstruation, and is distinct from normal vaginal bacteria. Therefore, the identification of clue cells serves as a significant indicator of bacterial vaginosis, helping guide clinicians in diagnosis and treatment decisions.