What is the gold standard for diagnosis of polycystic ovary syndrome?

The gold standard for diagnosing polycystic ovary syndrome (PCOS) is primarily based on the clinical criteria established by the Rotterdam criteria, which includes the presence of at least two of the following three features: oligomenorrhea or amenorrhea, clinical or biochemical signs of hyperandrogenism, and polycystic ovaries on ultrasound. This approach emphasizes the importance of a comprehensive clinical assessment, incorporating patient history, physical examination, and hormonal symptoms.

While ultrasound can be a valuable tool in identifying the presence of polycystic ovaries, it is not solely sufficient for diagnosis unless combined with clinical findings. Hormonal assessments can aid in evaluating levels of androgens and other hormones, but they also do not provide a complete picture without the context of clinical symptoms. Hysteroscopy involves visualizing the interior of the uterus and is not a standard procedure for diagnosing PCOS.

Thus, considering the multifaceted nature of PCOS and the reliance on clinical symptoms as outlined in established diagnostic criteria, clinical evaluation remains the cornerstone for diagnosis.