Chronic villus sampling can be performed at what gestational age?

Chorionic villus sampling (CVS) is a prenatal diagnostic procedure used to obtain a sample of the placental tissue (chorionic villi) for genetic analysis. The appropriate gestational age for performing CVS is typically between 10 to 12 weeks of gestation. This timing allows clinicians to obtain a sufficient amount of tissue for analysis while minimizing the risk of complications associated with the procedure.

Performing CVS before 10 weeks can increase the risk of complications, including a higher incidence of miscarriage compared to procedures conducted within the recommended time frame. Additionally, at this early stage, the placental tissue may not yet be mature enough for reliable sampling and analysis.

After 12 weeks, there are alternative tests available, such as amniocentesis, but CVS is specifically favored between 10-12 weeks for its distinct advantages, including earlier diagnosis capability and fewer risks than later procedures. Thus, the 10 to 12-week window represents the optimal time for the procedure to be performed, making it the correct answer.